NeMO Identifier: Collection

NeMO ID: nemo:dat-zngw2c8

  • Collection Name: Transcriptional impacts of substance use disorder and HIV on human ventral midbrain neurons and microglia
  • Short Name: Transcriptional impacts of substance use disorder and HIV (Wilson et al. 2025)
  • Programs: scorch

COLLECTION METADATA

  • Description:
  • Collection Type: Static
  • Taxa: human
  • Assays: transcriptome
  • Anatomical Regions: midbrain
  • Modalities:
  • Techniques: 10x chromium 3' v3 sequencing , gwas
  • Specimen Type:
  • Keywords: scorch , Substantia nigra , postmortem , HIV , substance use disorder , opioids , cocaine , single-nucleus RNA sequencing
  • Contact: Alyssa M. Wilson
  • Grant Numbers: 1U01DA053600
  • Funding Agency: NIDA
  • URL Protocol:
  • Data Access: open
  • Data License: Public data available under CC BY 4.0; controlled access data subject to data use certification

Contributors

Name Organization ORCID
Alyssa M. Wilson Icahn School of Medicine at Mount Sinai 0000-0002-3822-5200
Michelle Jacobs Icahn School of Medicine at Mount Sinai
Aditi Valada Icahn School of Medicine at Mount Sinai
Schahram Akbarian Icahn School of Medicine at Mount Sinai 0000-0001-7700-0891
Susan Morgello Icahn School of Medicine at Mount Sinai 0000-0001-7729-245X
Jacinta Murray
Evan Gilmore
Tova Y. Lambert

Project(s) this Collection Belongs To

ID Title
nemo:prj-q1zaxda Single nuclei transcriptome profiling in addiction circuitry of the HIV+ brain

Brain Region(s) of Interest

Name
midbrain

Child Collections

Collection ID Name Type Short Name Submission Status
nemo:dat-gi4tkn3 Transcriptional impacts of substance use disorder and HIV on human ventral midbrain neurons and microglia: Analysis 10xv3 files

Documentation


Data Citation:

Wilson, A.M., Jacobs, M.M., Lambert, T.Y. et al. Transcriptional impacts of substance use disorder and HIV on human ventral midbrain neurons and microglia. Nat Commun 16, 9123 (2025). https://doi.org/10.1038/s41467-025-64193-5