NeMO Identifier: Collection

NeMO ID: nemo:dat-zngw2c8

  • Collection Name: Transcriptional impacts of substance use disorder and HIV on human ventral midbrain neurons and microglia
  • Short Name: Transcriptional impacts of substance use disorder and HIV (Wilson et al. 2025)
  • Programs: scorch

COLLECTION METADATA

  • Description:
  • Collection Type: Static
  • Taxa: human
  • Assays: transcriptome
  • Anatomical Regions: midbrain
  • Modalities:
  • Techniques: 10x chromium 3' v3 sequencing , gwas
  • Specimen Type:
  • Keywords: scorch , Substantia nigra , postmortem , HIV , substance use disorder , opioids , cocaine , single-nucleus RNA sequencing
  • Contact: Alyssa M. Wilson ORCID iD icon
  • Grant Numbers: 1U01DA053600
  • Funding Agency: NIDA
  • URL Protocol:
  • Data Access: open
  • Data License: Public data available under CC BY 4.0; controlled access data subject to data use certification

Contributors

Name Organization ORCID
Alyssa M. Wilson Icahn School of Medicine at Mount Sinai ORCID iD icon 0000-0002-3822-5200
Michelle Jacobs Icahn School of Medicine at Mount Sinai
Aditi Valada Icahn School of Medicine at Mount Sinai
Schahram Akbarian Icahn School of Medicine at Mount Sinai ORCID iD icon 0000-0001-7700-0891
Susan Morgello Icahn School of Medicine at Mount Sinai ORCID iD icon 0000-0001-7729-245X
Jacinta Murray
Evan Gilmore
Tova Y. Lambert

Project(s) this Collection Belongs To

ID Title
nemo:prj-q1zaxda Single nuclei transcriptome profiling in addiction circuitry of the HIV+ brain

Brain Region(s) of Interest

Name
midbrain

Child Collections

Collection ID Name Type Short Name Submission Status
nemo:dat-gi4tkn3 Transcriptional impacts of substance use disorder and HIV on human ventral midbrain neurons and microglia: Analysis 10xv3 files

Documentation


Data Citation:

Wilson, A.M., Jacobs, M.M., Lambert, T.Y. et al. Transcriptional impacts of substance use disorder and HIV on human ventral midbrain neurons and microglia. Nat Commun 16, 9123 (2025). https://doi.org/10.1038/s41467-025-64193-5