Single nucleus transcriptomic and epigenomic profiling of  mouse locus coeruleus norepinephrine and dorsal and median raphe serotonin neurons - fastq (BICAN-2026-09-RR-SCO MetaSnapshot)

Program
bican
Collection Type
Static
Keywords
Rapid Release 2026

As part of the BRAIN Initiative Cell Atlas Network, multiomic atlas of Mus musculus dorsal and median raphe serotonin cells and locus coeruleus norepinephrine cells generated using 10X Genomics Multiome sequencing of microdissected DR and MR and LC. This dataset is part of spatio-molecular profiling of DR and MR and LC neuronal populations and contains expression data from neighboring populations - fastq (BICAN-2026-09-RR-SCO MetaSnapshot)

Data citation
Dataset (fastq): Zhixiao Su, Polina Kosillo, Kanghoon Jung, Shuonan Chen, Mathew T. Summers, Alex Piet, Han Hou, Kenta M. Hagihara, Drew Friedmann, Olivia Ho-Shing, Madhav Kannan, Matthew I. Becker, Thomas Chartrand, Peter Grotz, Ella Hilton-VanOsdall, Margaret Lee, Rajvi Javeri, Samantha L. Tuggle, Naveen Ouellette, Holly Myers, Camilo Laiton, Kaelin Wulf, John Rohde, Alessio Buccino, Cameron Arshadi, Di Wang, Sharmishtaa Seshamani, Sonya Vasquez, Carolyn M. Eng, Douglas R. Ollerenshaw, Nick Dee, Tamara Casper, Windy Ho, Matthew Jungert, Atlas Jordan, Elliot Phillips, Anish Bhaswanth Chakka, Kamiliam Nasirova, Krista Blake, Audrey McCutcheon, Megan Koch, Maria Camila Vergara, Kimberly A. Smith, Tim Jarsky, Nicholas Lusk, Mara Rue, Xiaoyin Chen, Joshua H. Siegle, Adam K. Glaser, Brian R. Lee, Karel Svoboda, Yoh Isogai, Jayaram V. Chandrashekar, Jeremiah Y. Cohen (2026) Neuromodulation: Single nucleus transcriptomic and epigenomic profiling of mouse locus coeruleus norepinephrine and dorsal and median raphe serotonin neurons [Dataset - fastq]. Available from: https://assets.nemoarchive.org/nemo:col-9p2p1z6
Funding agency
NIMH
Grant numbers
R01MH134833
Access
open
License
CCBY4

Download URLs

  • Download BDBag https://data.nemoarchive.org/bdbags/BICAN/BICAN-2026-09-RR-SCO/col-9p2p1z6__BICAN__MetaSnapshot__2026-09-25__BICAN_Neuromodulation__aibs__nuclei__10X_genomics_multiome__house_mouse__demultiplexed_fastq__open__no_restriction.tgz 224 files 7,257.90 GB
    Raw BDBag

Anatomical Regions

  • Locus ceruleus
  • Dorsal nucleus raphe
  • Central linear nucleus raphe
  • Superior central nucleus raphe, medial part

Taxa

house mouse

Projects this collection belongs to

  • nemo:prj-pv9uoga
    Structure-function cell atlas for norepinephrine and serotonin neurons

Assays, Modalities & Techniques

Assays
multiome; chromatin multiome; transcriptome
Modalities
multimodal
Techniques
10X genomics multiome;atac-seq 10X genomics multiome;rnaseq

Child collections

  • nemo:col-degqkoc
    Single nucleus transcriptomic and epigenomic profiling of  mouse locus coeruleus norepinephrine and dorsal and median raphe serotonin neurons - fastq (BICAN-2026-09-RR-SCO Snapshot ATAC)
  • nemo:col-rr11ok0
    Single nucleus transcriptomic and epigenomic profiling of  mouse locus coeruleus norepinephrine and dorsal and median raphe serotonin neurons - fastq (BICAN-2026-09-RR-SCO Snapshot RNA)

Parent collections

  • nemo:col-uoip2ah
    Single nucleus transcriptomic and epigenomic profiling of  mouse locus coeruleus norepinephrine and dorsal and median raphe serotonin neurons - fastq (MetaCumulative)
    collection
  • nemo:col-i17zvqh
    BICAN Rapid Release Inventory: Single cell transcriptomics and epigenomics (BICAN-2026-09-RR-SCO)
    collection

Associated publications

No publications linked yet.

URL Protocols

No protocol URLs listed for this collection.

Contributors

No contributors listed for Single nucleus transcriptomic and epigenomic profiling of  mouse locus coeruleus norepinephrine and dorsal and median raphe serotonin neurons - fastq (BICAN-2026-09-RR-SCO MetaSnapshot) collection.

Cross-archive links

No cross-archive links listed for this collection.

Documentation & resources