Single nucleus transcriptomic profiling of mouse locus coeruleus norepinephrine neurons with projections to frontal cortex, cerebellum and spinal cord - fastq (BICAN-2026-09-RR-SCO Snapshot)

Program
bican
Collection Type
Static
Specimen Type
nuclei
Keywords
Rapid Release 2026

As part of the BRAIN Initiative Cell Atlas Network, transcriptomic atlas of Mus musculus locus coeruleus norepinephrine neurons generated using retrograde labeling with injections targeting frontal cortex, cerebellum or spinal cord, followed by FACS sorting of fluorescently labeled nuclei and SMART-seq V4 sequencing. This dataset is part of spatio-molecular profiling of locus coeruleus and sub-coeruleus norepinephrine neuronal populations - fastq (BICAN-2026-09-RR-SCO Snapshot)

Data citation
Dataset (fastq): Zhixiao Su, Polina Kosillo, Kanghoon Jung, Shuonan Chen, Mathew T. Summers, Alex Piet, Han Hou, Kenta M. Hagihara, Drew Friedmann, Olivia Ho-Shing, Madhav Kannan, Matthew I. Becker, Thomas Chartrand, Peter Grotz, Ella Hilton-VanOsdall, Margaret Lee, Rajvi Javeri, Samantha L. Tuggle, Naveen Ouellette, Holly Myers, Camilo Laiton, Kaelin Wulf, John Rohde, Alessio Buccino, Cameron Arshadi, Di Wang, Sharmishtaa Seshamani, Sonya Vasquez, Carolyn M. Eng, Douglas R. Ollerenshaw, Nick Dee, Tamara Casper, Windy Ho, Matthew Jungert, Atlas Jordan, Elliot Phillips, Anish Bhaswanth Chakka, Kamiliam Nasirova, Krista Blake, Audrey McCutcheon, Megan Koch, Maria Camila Vergara, Kimberly A. Smith, Tim Jarsky, Nicholas Lusk, Mara Rue, Xiaoyin Chen, Joshua H. Siegle, Adam K. Glaser, Brian R. Lee, Karel Svoboda, Yoh Isogai, Jayaram V. Chandrashekar, Jeremiah Y. Cohen (2026) Neuromodulation: Single nucleus transcriptomic profiling of mouse locus coeruleus norepinephrine neurons with projections to frontal cortex, cerebellum and spinal cord [Dataset - fastq]. Available from: https://assets.nemoarchive.org/nemo:col-oxwf5dn
Funding agency
NIMH
Grant numbers
R01MH134833
Access
open
License
CCBY4

Download URLs

  • Download BDBag https://data.nemoarchive.org/bdbags/BICAN/BICAN-2026-09-RR-SCO/col-oxwf5dn__BICAN__Snapshot__2026-09-25__BICAN_Neuromodulation__aibs__nuclei__SSv4__house_mouse__demultiplexed_fastq__open__no_restriction.tgz 2,766 files 57.34 GB
    Raw BDBag

Anatomical Regions

  • Locus ceruleus

Taxa

house mouse

Projects this collection belongs to

  • nemo:prj-pv9uoga
    Structure-function cell atlas for norepinephrine and serotonin neurons

Assays, Modalities & Techniques

Assays
transcriptome
Modalities
transcriptome
Techniques
smart-seq v4

Child collections

No child collections listed for Single nucleus transcriptomic profiling of mouse locus coeruleus norepinephrine neurons with projections to frontal cortex, cerebellum and spinal cord - fastq (BICAN-2026-09-RR-SCO Snapshot) collection.

Parent collections

  • nemo:col-ovvr5bv
    Single nucleus transcriptomic profiling of mouse locus coeruleus norepinephrine neurons with projections to frontal cortex, cerebellum and spinal cord - fastq (Cumulative)
    collection
  • nemo:col-i17zvqh
    BICAN Rapid Release Inventory: Single cell transcriptomics and epigenomics (BICAN-2026-09-RR-SCO)
    collection

Associated publications

No publications linked yet.

URL Protocols

Contributors

No contributors listed for Single nucleus transcriptomic profiling of mouse locus coeruleus norepinephrine neurons with projections to frontal cortex, cerebellum and spinal cord - fastq (BICAN-2026-09-RR-SCO Snapshot) collection.

Cross-archive links

No cross-archive links listed for this collection.

Documentation & resources